Integrated Treatment for Posttraumatic Stress Disorder and Substance Abuse in Young Adults

UConn Health

Status: Completed

Conditions: Posttraumatic Stress Disorder; Substance Use Disorder

Treatments: Behavioral: Prolonged Exposure with Contingency Management; Behavioral: Standard Care

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT02667119

K23DA034879 (U.S. NIH Grant/Contract)

16-101-2

Details and patient eligibility

About

The purpose of the study is to determine the safety and efficacy of an integrated treatment for substance abuse and posttraumatic stress disorder for young adults. The integrated treatment includes two established psychosocial treatments for substance abuse (Contingency Management) and posttraumatic stress disorder (Prolonged Exposure therapy).

Enrollment: 27 patients

Sex: All

Ages: 18 to 25 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18-25 years old
• meets diagnostic criteria for substance use disorder
• meets diagnostic criteria for full or subthreshold posttraumatic stress disorder
• currently able to provide a urine drug screen that is negative for cocaine, prescription opiates, and non-prescribed methadone or provided this type of screen in the past 60 days
• speaks English

Exclusion criteria

• significant cognitive impairment or serious uncontrolled psychiatric problem (other than posttraumatic stress disorder)
• in recovery from pathological gambling or current pathological gambling diagnosis
• in a current domestic violence relationship

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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27 participants in 2 patient groups

Prolonged Exposure + Contingency Management

Experimental group

Description:

Standard services plus Prolonged Exposure and Contingency Management

Treatment:

Behavioral: Standard Care

Behavioral: Prolonged Exposure with Contingency Management

Standard Care

Active Comparator group

Description:

Standard substance abuse treatment services

Treatment:

Behavioral: Standard Care