Integrating Molecular Pathology, Radiology, and Genetics to Improve Breast Cancer Risk

Mayo Clinic

Status: Enrolling

Conditions: Breast Carcinoma

Treatments: Other: Non-Interventional Study

Study type: Observational

Funder types: Other

Identifiers

NCT07207564

23-009436 (Other Identifier)

NCI-2025-06873 (Registry Identifier)

Details and patient eligibility

About

The purpose of this research is to better understand how benign breast diseases might lead to breast cancer, focusing on genetic factors and including a diverse range of participants to improve future diagnosis and treatment.

Enrollment: 4,500 estimated patients

Sex: Female

Ages: 18 to 100 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Female patients, ages 18 to 100 years
• Had a benign breast biopsy at Mayo Clinic between 2002-2022

Exclusion criteria

• All male patients
• Prior or concomitant diagnosis of BC
• Diagnosis of BC within six months of benign breast disease
• Denial of research authorization
• Concurrent or post-biopsy bilateral prophylactic mastectomy

Trial design

4,500 participants in 1 patient group

Observational

Description:

Participants complete a questionnaire, undergo collection of saliva or blood samples, and have their medical records reviewed on study.

Treatment:

Other: Non-Interventional Study