Integrative Nutrition Care Plan for the Patient With Liver and Colorectal Cancer

Taipei Medical University

Status: Completed

Conditions: Cancer of Colon; Malnutrition; Cancer of Liver; Nutrition Aspect of Cancer

Treatments: Combination Product: Nutritional consultant + Liquid supplement + Powdered supplement 1 and 2; Behavioral: Nutritional consultant; Dietary Supplement: Nutritional consultant + High-calorie, high-protein liquid nutrition supplement

Study type: Interventional

Funder types: Other

Identifiers

NCT05030090

N202105003

Details and patient eligibility

About

At present, the families of cancer patients are lack knowledge and experience of nutritional care after discharge. As a result, cancer patients often suffer from low nutritional status after being discharged from the hospital.

Full description

This study intends to design a home nutrition care plan to explore the effect of a home nutrition care plan on the nutritional status of patients with liver cancer and colorectal cancer at risk of malnutrition. Malnutrition or side effects often lead to natural food intake for patients. It is not enough to meet the nutritional requirements, so it is matched with dietary products to help patients more easily meet their nutritional requirements. Supplements are used to alleviate patients' side effects. It is hoped that they can help patients improve their nutritional status.

Enrollment: 66 patients

Sex: All

Ages: 20 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Patients with liver cancer or colorectal cancer stage I to III
2. Not suffering from other carcinomas in situ at the same time
3. Will undergo surgery or non-surgical cancer treatment
4. Can move, read and answer questions by itself
5. At least one social support (family or friend) to assist and support the patient to complete the trial
6. According to the aPG-SGA, the assessment score is between 4 ~ 9
7. The patient or caregiver can cooperate with the dietitian to track and answer related questions asked by the dietitian in a remote way through communication software or telephone every week.
8. Able to adjust diet or take nutrition and supplements daily with the guidance of a nutritionist
9. Be able to cooperate with doctors and the beginning of the study and monthly return visits and blood tests for health insurance items

Exclusion criteria

1. Perform organ transplantation or palliative care
2. Hepatic encephalopathy
3. History of cardiovascular and cerebrovascular diseases
4. Severe organ failure of the heart, breathing, or kidneys
5. History of digestive tract inflammation or ulcer
6. Severe mental illness
7. An active infectious diseases
8. Those who can only use intravenous nutrition and cannot use enteral nutrition
9. People who are allergic to product ingredients (milk, soy, or mango and their products)
10. Unwilling to cooperate with dietitians to make dietary adjustments or supplement nutrition and supplements
11. Unwilling to actively treat cancer

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

66 participants in 3 patient groups

Control group

Active Comparator group

Description:

1. Consulted by the dietitian using communication software (Line) or telephone. 2. At 0.5, 1, 1.5, 2, 2.5, and 3 months will track the biochemical data, assess nutritional status and quality of life. 3. The nutrition care plan period will be three months.

Treatment:

Behavioral: Nutritional consultant

Nutrition care plan group A

Experimental group

Description:

1. Consulted by the dietitian using communication software (Line) or telephone. 2. Implement a daily diet with a concentrated high-calorie and high-protein liquid supplement 3. At 0.5, 1, 1.5, 2, 2.5, and 3 months will track the biochemical data, assess nutritional status and quality of life. 3.The nutrition care plan period will be three months.

Treatment:

Dietary Supplement: Nutritional consultant + High-calorie, high-protein liquid nutrition supplement

Behavioral: Nutritional consultant

Nutrition care plan group B

Experimental group

Description:

1. Consulted by the dietitian using communication software (Line) or telephone. 2. Implement a daily diet with a concentrated high-calorie and high-protein liquid supplement and powdered supplement 1 and nutritional products and powdered supplement 2 3. At 0.5, 1, 1.5, 2, 2.5, and 3 months will track the biochemical data, assess nutritional status and quality of life. 4. The nutrition care plan period will be three months.

Treatment:

Behavioral: Nutritional consultant

Combination Product: Nutritional consultant + Liquid supplement + Powdered supplement 1 and 2