ClinicalTrials.Veeva

Menu

Integrative Omics Analysis for Colorectal Cancer and Metastasis

F

fan li

Status

Enrolling

Conditions

Colorectal Cancer

Treatments

Other: Integrative omics

Study type

Observational

Funder types

Other

Identifiers

Details and patient eligibility

About

The pathogenesis of Colorectal cancer (CRC) metastasis remains unclear.We collect clinical data from our center and use Integrative omics to analyze and predict candidate biomarkers of colorectal cancer and distant metastasis.

Full description

Colorectal cancer (CRC), one of the most common malignant cancer around the world, CRC patients with distant metastasis. However, the pathogenesis of metastasis remains unclear. Integrative omics have begun to enable personalized medicine at an extraordinarily detailed molecular level. All patients with colorectal cancer and metastasis in our center who meet the inclusion criteria and exclusion criteria will be enrolled. The specimen collected by surgery and clinical data will be collected . We use Integrative omics such as RNA-sequencing,ATAC-seq(Assay for Transposase-Accessible Chromatin using sequencing), CUT&Tag( Cleavage Under Targets and Tagmentation)to analyze and predict candidate biomarkers of colorectal cancer and distant metastasis. This study will contribute to understanding the molecular mechanism of CRC metastasis in depth and contribute to the discovery of new appropriate molecular diagnostic and therapeutic targets, and more accurately prognose long term outcome in patients with CRC.

Enrollment

20 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • colorectal adenocarcinoma by biopsy。
  • at least 1 metastasis lesion comfirmed by at least 1 kind of imaging examination (CT, MRI and PET-CT )

Exclusion criteria

  • recent diagnosis with other malignancies
  • can not tolerate the surgery
  • history of serious mental illness
  • pregnancy or lactating women
  • the researchers believe the patients should not enrolled in

Trial design

20 participants in 1 patient group

colorectal cancer with metastasis
Description:
colorectal cancer patients with at least one distant metastasis(liver, lung)
Treatment:
Other: Integrative omics

Trial contacts and locations

1

Loading...

Central trial contact

fan li, MD

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2024 Veeva Systems