Intelligence Changes Following Minor Surgery

Shanghai Jiao Tong University

Status: Withdrawn

Conditions: Phimosis; Inguinal Hernia; Hypospadia

Study type: Observational

Funder types: Other

Identifiers

NCT01483313

RenJiH-20111005

Details and patient eligibility

About

Animal studies showed that many general anesthetics might result in neuron apoptosis and neurocognitive impairment in the developing brain. However results from human studies are conflicted. In present study, the investigators examined the association between early exposure to anesthesia and surgery for minor surgery and intelligence changes in adolescence using the Wechsler Intelligence Scale for Children.

Sex: Male

Ages: 6 to 16 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Born from 1995
2. Male
3. Parents or guardian agree to attend this study
4. Undergone minor surgery (Repair of hypospadias, phimosiectomy, cryptorchidectomy or cryptorchidopexy and repair of inguinal hernia)
5. Children who scarify the No.1 to No.3 but no experience of any surgery.
6. Those who undergone minor surgery in Renji Hospital 4-6years ago.

Exclusion criteria

1. Any congenital central nervous system diseases
2. Any congenital heart diseases
3. Any congenital dysgnosia
4. Birth weight less than 2kg
5. Ever been hypoxic encephalopathy when birth