Intensive Strength Training in Children With Cerebral Palsy - Effect on Hand Function

St. Olavs Hospital

Status and phase: Completed; Phase 2

Conditions: Cerebral Palsy

Treatments: Drug: Botulinum Toxin A; Behavioral: Resistance training

Study type: Interventional

Funder types: Other

Identifiers

NCT00467207

06/1553

Details and patient eligibility

About

The objective of this study is to gain more knowledge about the association between muscle weakness, spasticity and motor control in children with cerebral palsy, and its relationship to hand function.

Enrollment: 10 patients

Sex: All

Ages: 10 to 17 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosed spastic hemiplegic or diplegic cerebral palsy, reduced handfunction.
• Indication for treatment with Botulinum Toxin A
• Score 3 on House Classification of Upper-Extremity Functional Use
• Score 3 or better on Manual Ability Classification System

Exclusion criteria

• surgery within the last two years
• Treatment with Botulinum Toxin within the last six months

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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10 participants in 2 patient groups

BoNT A

Active Comparator group

Description:

Botulinum toxin A injections in muscles of the arm (biceps brachii and brachialis)

Treatment:

Drug: Botulinum Toxin A

Resistance training

Experimental group

Description:

8 weeks resistance training

Treatment:

Behavioral: Resistance training

Drug: Botulinum Toxin A