Intent of Surgery for IPMN

NYU Langone Health

Status: Enrolling

Conditions: Intraductal Papillary Mucinous Neoplasm

Study type: Observational

Funder types: Other

Identifiers

NCT07216521

25-00989

Details and patient eligibility

About

This multicenter retrospective observational cohort study seeks to:

1. Classify surgical intent in patients with resected Intraductal Papillary Mucinous Neoplasms (IPMN) and quantify the proportion of IPMN-associated cancers diagnosed as overt pancreatic cancer with incidental IPMN association on pathology.
2. Compare clinicopathologic features and outcomes between surveillance-detected and incidentally detected IPMN-derived pancreatic cancers.
3. Revise and redefine risk features limited to patients undergoing surgery for IPMN-related indications, identifying optimal predictors of malignant IPMN (high-grade dysplasia or invasive cancer).

Enrollment: 2,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients (18 years old of greater) who underwent surgical resection for IPMN (including low-, high-grade dysplasia, or invasive carcinoma) between July 1, 2015 and July 1, 2025.

Exclusion criteria

• Patients with concomitant pancreatic ductal adenocarcinoma (PDAC)

Trial design

2,000 participants in 1 patient group

Patients who underwent surgical resection for IPMN

Description:

Pathology reports on patients (18 years old of greater) who underwent surgical resection for IPMN will be accessed for analysis.