Interactions Between Cocaine and Ethanol and Disulfiram - 1

National Institutes of Health (NIH)

Status and phase: Unknown; Phase 1

Conditions: Cocaine-Related Disorders; Alcohol-Related Disorders

Treatments: Drug: Disulfiram

Study type: Interventional

Funder types: NIH

Identifiers

NCT00094289

NIDA-MDS-0003-1

Details and patient eligibility

About

The purpose of this study is to assess potential interactions between intravenous cocaine and ethanol and oral disulfiram.

Full description

This is a two-site, double blind, placebo-controlled inpatient study to determine the cardiovascular and psychiatric safety of alcohol use in cocaine-dependent subjects who had used cocaine after treatment with disulfiram.

Sex: All

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Must meet DSM-4 criteria for cocaine abuse or dependence and are not seeking treatment.
• Ability to verbalize understanding of consent form and provide written informed consent and verbalize willingness to complete study procedures; be able to comply with protocol requirements.

Exclusion criteria

• Please contact site for more information.