Interactions Between Environmental Exposures and Gut Microbiota in Early Life

Peking University

Status: Enrolling

Conditions: Infant Development

Treatments: Other: delivery mode

Study type: Observational

Funder types: Other

Identifiers

NCT06479928

PKUPH-X1

Details and patient eligibility

About

Recruit the mothers and their infants who bron in Peking University People's Hospital from 2023 to 2026, to evaluate the interaction between environmental exposure and gut microbiota.

Enrollment: 756 estimated patients

Sex: All

Ages: 1 day to 24 months old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Pregnant woman

   • aged 20-40 years old
   • natural conception
   • single pregnancy
   • gestational age ≥36 weeks

2. Newborn

   • normal Apgar score
   • no serious congenital diseases

Exclusion criteria

Trial design

756 participants in 2 patient groups

Mother-infant cohorts (Cesarean section)

Description:

Delivery mode, Cesarean section

Treatment:

Other: delivery mode

Mother-infant cohorts (Natural delivery)

Description:

Delivery mode, Natural delivery

Treatment:

Other: delivery mode