INTERCOSTAL NERVE BLOCK: Efficacy of CINB for Patients With Multiple Rib Fractures

Zachary Warriner

Status and phase: Enrolling; Phase 4

Conditions: Rib Fractures

Treatments: Drug: Ropivacaine; Drug: Non steroidal anti-inflammatory drug and opioids

Study type: Interventional

Funder types: Other

Identifiers

NCT05642026

SURMI-22-INTERCOSTAL-NB

Details and patient eligibility

About

This is a prospective, randomized, non-blinded study comparing CINB plus medical therapy versus standard medical care (non-steroidals and opioids intravenous/oral inpatient and oral outpatient) alone for patients with multiple rib fractures. The objective of this study is to analyze the effect of continuous intercostal nerve block (CINB) in the treatment of patients admitted to the adult trauma service with rib fractures. The effectiveness of CINB as adjunctive treatment will be compared to standard medical therapy involving nonsteroidal and intravenous/oral opioid medications.

Enrollment: 180 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Subjects will be at least 18 years old
• Subjects will have 2 or more identified rib fractures
• Subjects will be willing to provide informed consent for procedure
• Subjects will be identified as appropriate for initiation of continuous nerve block therapy for treatment of rib fracture associated pain.

Exclusion criteria

• Documented allergy to study medication
• Epidural catheter use
• Prisoners
• Refusal of CINB therapy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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180 participants in 2 patient groups

continuous intercostal nerve block (CINB)

Experimental group

Description:

patients admitted to the adult trauma service with rib fractures who are receiving CINB

Treatment:

Drug: Non steroidal anti-inflammatory drug and opioids

Drug: Ropivacaine

standard medical care

Active Comparator group

Description:

patients admitted to the adult trauma service with rib fractures who are receiving standard medical care

Treatment:

Drug: Non steroidal anti-inflammatory drug and opioids