Interdialytic Resistance Exercises in with Chronic Kidney Diseases

Cairo University (CU)

Status: Active, not recruiting

Conditions: Chronic Kidney Diseases

Treatments: Procedure: intra-dialytic exercise program associated with medical treatment; Procedure: inter-dialytic combined exercise program with their medications

Study type: Interventional

Funder types: Other

Identifiers

NCT06862336

012/005019

Details and patient eligibility

About

Fifty chronic kidney disease patients' ages will range from 40 to 55 years. They will be selected from the dialysis unit. received intra-dialytic combined exercise program for 8 weeks(3 sessions/week), with their medical treatment.

Enrollment: 50 estimated patients

Sex: All

Ages: 40 to 55 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Fifty patients with CKD, are on hemodialysis for longer than threemonths 3 sessions/ week.
2. Theirageswillrangefrom40 to 55yearsold.
3. Their body mass index is more than 18.5 and less than 29.9 %.

3-All patients have hemodynamic stability over the month before beginning the program.

Exclusion criteria

• 1. Severe Chest diseases(either obstructive or restrictive). 2. Clinical signs of a severe cardiac event.(eg, severe atherosclerosis, congestive heart failure), 3. Severepsychiatricorcognitiveimpairment,whounabletofollowcomment. 4. Neurological disorders affecting respiratory muscles or any muscular dystrophies(cervical disc or bulge).

  2. Patients with severe self-limiting illness (e.g., cancer). 6. peripheral artery disease in lower extremities. 7. Systolic blood pressure < 180 mmHg, diastolic blood pressure more than 105 mmHg, or heart rate above 120 bpm during dialysis.

  3. Patient with uncontrolled- diabetes.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

50 participants in 2 patient groups, including a placebo group

Group A

Experimental group

Description:

twenty-five patients with CKD will receive intra-dialytic combined exercise program for8 weeks(3 sessions/week), with their medical treatment.

Treatment:

Procedure: intra-dialytic exercise program associated with medical treatment

Group B

Placebo Comparator group

Description:

twenty-five patients with CKD will receive the inter-dialytic combined exercise program with their medications.

Treatment:

Procedure: inter-dialytic combined exercise program with their medications