Interest of a Post-operative Ultrasound With Systematic Use of Ultrasonic Contrast in the Follow-up of Aortic Endoprosthesis: Prospective Study at the University Hospital of Nice (Ultra_Evar)

Centre Hospitalier Universitaire de Nice

Status

Completed

Conditions

Aneurysm, Abdominal Aortic

Treatments

Other: écho-doppler with ultrasonar Sonovue® injection

Study type

Interventional

Funder types

Other

Identifiers

NCT04196543

19-AOI-05

Details and patient eligibility

About

This is a prospective study conducted on a population with an aortic endoprosthesis in the context of an abdominal aortic aneurysm. The study's objective is to standardize the ultrasound methodology in the monitoring of aortic endoprosthesis in immediate post-operative care by comparing the results with CT-scan (gold standard). To improve ultrasound methodology, the investigators propose to use the VESMA protocol for ultrasound diameter measurement at four incidences. In addition, the use of ultrasonic contrast agents increases the accuracy of vascular structures, the quality of the ultrasound blood flow image and the duration of signal enhancement. This makes it possible to visualize small gauge vessels and those with slow flows. In this way, the investigators could improve the ultrasound technique for measuring aneurysm bag diameters and endoleak detection. Moreover, the toxicity of iodinated contrast agents is the third cause of acute renal failure in hospitalized patients and is all the more frequent when the investigators increase injections. Improving the quality of ultrasound investigations for the monitoring of aortic endoprosthesis would therefore allow us to reduce the number of CT-scan performed in this population and thus reduce irradiation and the injection of nephrotoxic products. Thereby, the investigators would like to integrate the technique into the systematic follow-up of patients who have benefited from the placement of an aortic endoprosthesis by replacing the CT-scan.

Enrollment

40 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients over 18 years of age.
Abdominal aortic aneurysm treated with aortic stent.
Signature of informed consent.
Person affiliated or beneficiary of a social security scheme

Exclusion criteria

Hypersensitivity to sulphur hexafluoride or to these excipients (Macrogol 4000, Distearoylphosphatidylcholine, Dipalmitoylphosphatidylglycerol sodé, Palmitic acid).
Right-left shunt patient
Patient with severe pulmonary hypertension (pulmonary blood pressure > 90 mm Hg),
Patient with uncontrolled systemic hypertension
Adult patients with respiratory distress syndrome.
Dobutamine patient in patients with a pathology suggesting cardiac instability
Hypercoagulation, recent thromboembolic accident
Fenestrated aortic stent
Pregnant or nursing woman.
Severe heart failure.
Person deprived of liberty by judicial or administrative decision.
Person subject to legal protection.