Interest of Eye Movement Measurements in the Comprehension of Dry Eyes Symptoms (BOSO)

Fondation Ophtalmologique Adolphe de Rothschild

Status: Completed

Conditions: Blinking; Dry Eye Syndromes

Treatments: Device: Infrared oculography

Study type: Observational

Funder types: NETWORK

Identifiers

NCT02851654

CLL_2013-16

Details and patient eligibility

About

Dry eye syndrome is a benign situation however its impact on patient's quality of live and on health system is not trivial. One problem is the lack of correlation between patient's symptoms and physical sign observed on slit lamp examination. Eye blinking is a parameter of increased interest in this pathology particularly its frequency. To date no treatment of dry eye syndrome has a proven impact on eye blinking frequency. However recording of blinks has mostly been performed on short duration (3 to 5 minutes) and the distribution of intervals between 2 blinks is not gaussian but exponential. In this study, it is proposed to use modern eye-movement recorder to measure the blink frequency on longer duration (12 minutes) while reading on a screen computer and during a face-to-face interview before and after treatment of meibomian gland dysfunction responsible of moderate to severe dry eye syndrome.

Enrollment: 24 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Moderate to severe dry eye syndrome (Ocular Surface Disease Index> 30) following a meibomian gland dysfunction
• Not yet properly treated for a meibomian gland dysfunction

Exclusion criteria

• History of other ophthalmological or neurological disease
• Pregnant or breastfeeding women
• Patient under 18 years old
• Patient under legal protection

Trial design

24 participants in 1 patient group

Dry eye syndrome

Description:

Meibomian gland dysfunction responsible of moderate to severe dry eye syndrome

Treatment:

Device: Infrared oculography