Interest of Instantaneous Fluctuations of Pupillary Diameter for Pain Evaluation in Intensive Care Sedated Patients.

Centre Hospitalier Universitaire de Saint Etienne

Status: Completed

Conditions: Intubation Complication

Treatments: Other: Datas analysed by medical records

Study type: Observational

Funder types: Other

Identifiers

NCT05633069

IRBN412014/CHUSTE

Details and patient eligibility

About

New pain assessment parameter, called the Variation Coefficient of Pupillary Diameter (VCPD) described. This parameter allows evaluating the pain of patients during uterine contractions in obstetrical labor, and postoperatively in recovery room.

This parameter also allows evaluating the level of pain in Intensive Care Unit (ICU), in intubated or tracheotomized patients moderately sedated (Riker score 3 or 4).

Full description

This study propose to recalculate the Variation Coefficient of Pupillary Diameter (VCPD) from pupil recordings performed in the Intensive Care Unit (ICU) in 2015-2016 and kept in the patients' records. From there, the Variation Coefficient of Pupillary Diameter (VCPD) will compare to the Behavioral Pain Scale (BPS), considered the gold standard pain assessment

Enrollment: 120 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• hospitalized in the surgical Intensive Care Unit (ICU) of the University Hospital of Saint-Etienne between September 2015 and August 2016 for medical-surgical pathologies
• requiring orotracheal intubation or tracheostomy
• and presenting a Riker sedation score of 3 or 4.

Exclusion criteria

• cerebral palsy
• curarization
• paraplegia or tetraplegia
• intensive care neuromyopathy
• ocular pathology
• history of severe dysautonomic disease that could influence the evaluation of the Behavioral Pain Scale (BPS) or Variation Coefficient of Pupillary Diameter (VCPD) score
• receiving antiarrhythmic treatment that could make the interpretation of the results difficult
• on metoclopramide, droperidol, clonidine, or dexmedetomidine, which are known to alter the pupil dilation reflex.

Trial design

120 participants in 1 patient group

Patients requiring orotracheal intubation or tracheostomy

Description:

Patients hospitalized in the surgical Intensive Care Unit (ICU) of the University Hospital of Saint-Etienne between September 2015 and August 2016 for medical-surgical pathologies, requiring orotracheal intubation or tracheostomy, and presenting on the day of recording a Riker sedation score of 3 or 4 will be included. Datas analysed by medical records.

Treatment:

Other: Datas analysed by medical records