Interest Of Renal Elastography In Children As A Diagnostic Tool Of Renal Fibrosis: Confrontation To Histological Features Of Renal Biopsies

Public Assistance-Hospitals of Marseille (AP-HM)

Status

Completed

Conditions

RENAL FIBROSIS

Treatments

Procedure: Elastography

Study type

Interventional

Funder types

Other

Identifiers

NCT01613625

2010-10

2010-A00950-39

Details and patient eligibility

About

Elastography is a emerging imaging technique that has demonstrated high reliability in the assessment of tissues stiffness and quantification of fibrosis particularly in adult's livers. This ultrasound exploration has no secondary effects. There is no study published in the pediatric population concerning the role of ultrasound elastrography in kidney. The aim of this study is to look for a correlation between the elastography's results and the kidney fibrosis on children who have to undergo a renal biopsy. Elastography may play a potential diagnostic and/or prognostic role in the management of these patients which would limit invasive biopsy procedures.

Enrollment

106 patients

Sex

All

Ages

5 to 18 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Male children or feminine from 5 to 18 years old to whom is indicated a renal biopsy by the néphrologue paediatrician whatever is the initial pathology, whatever are one or several current or previous treatments and whatever is their associated comorbidity

Exclusion criteria

Children of less than 5 years old or more than 18 years
Children for whom a draining renal biopsy is not or more indicated by néphrologues
Refusal or withdrawal of the consent lit by the holders of the exercise of the parental authority or by the child if he is capable of receiving the information
Contraindication in the realization of a draining renal biopsy (current infection, disorder of the coagulation.)