ClinicalTrials.Veeva

Menu

Interest of the T2 * Sequence in MRI for the Diagnosis of Migraine Aura in the Acute Phase. (MARIE)

T

Toulouse University Hospital

Status and phase

Completed
Phase 4

Conditions

Migraine Aura

Treatments

Diagnostic Test: MRI control
Combination Product: MRI
Other: telephone consultation

Study type

Interventional

Funder types

Other

Identifiers

NCT03689361
RC31/16/8249
2017-004091-60 (EudraCT Number)

Details and patient eligibility

About

investigators hypothesize that T2 * vein abnormalities are frequent and are specific to the migraine aura.

Full description

The diagnosis of migraine aura is now based solely on clinical criteria and the assertion of the diagnosis on these clinical criteria alone proves difficult in the acute phase. Added to this difficulty, the symptomatology of a migraine aura can sometimes be similar to that of a stroke, so a diagnosis can be poorly established, resulting in poor patient care. The possibility of making the positive diagnosis of migraine aura on a routine MRI sequence, T2 *, would be an important advance for the management of these patients

Enrollment

60 patients

Sex

All

Ages

18 to 55 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patients aged 18 to 55 years

  • Admitted to the Neuro-Vascular Intensive Care Unit for Acute Focused Neurological Symptoms and MRI

    • less than 4 hours 30 minutes after onset of symptoms if symptoms persist during admission
    • less than two hours after the disappearance of symptoms if the patient arrives asymptomatic
  • Affiliated to a social protection scheme.

  • Having given their informed consent

Exclusion criteria

  • Patients with neurological signs pointing to vertebrobasilar localization (vertigo, diplopia) or with a disorder of consciousness
  • Presence of recent explanatory abnormalities on the MRI to make a diagnosis compatible with the initial neurological symptomatology (visible stroke in diffusion, cerebral hemorrhage, tumor, arteriovenous malformations).
  • Potential strong cause of stroke known or discovered at the arrival of the patient, in particular stenosis of a cervical or intracranial artery upstream of the cerebral zone may correspond to the symptoms and emboligenic heart disease type atrial fibrillation.
  • Pregnant women - Patients with a contraindication for MRI.
  • Patients benefiting from a system of legal protection (tutelage,

Trial design

Primary purpose

Diagnostic

Allocation

Non-Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

60 participants in 2 patient groups

with migraine aura.
Other group
Description:
patient with migraine aura detected by MRI, then MRI control 3 month after
Treatment:
Combination Product: MRI
Diagnostic Test: MRI control
without migraine aura
Other group
Description:
patient without migraine aura detected by MRI, then telephone consultation 3 month after
Treatment:
Other: telephone consultation

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2024 Veeva Systems