Interest of Tracheal Extubation in Positive Pressure on Postoperative Oxygenation in Adult Digestive Surgery: Prospective Randomized Study ExPress

University Hospital, Rouen

Status

Unknown

Conditions

Patients Undergoing Digestive Surgery With Orotracheal Intubation

Treatments

Procedure: positive pressure extubation

Study type

Interventional

Funder types

Other

Identifiers

NCT04381949

2019/0351/HP

Details and patient eligibility

About

Evaluation of a postoperative tracheal extubation protocol under positive pressure in accordance with international recommendations.

Two arms: the first with "classic" extubation with disconnection of the respirator and the second with extubation without disconnection of the respiratory, as recommended.

Computer Randomization with a 1: 1 ration

Enrollment

208 estimated patients

Sex

All

Ages

18 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Age> 18 and <80
Patient going to benefit from general anesthesia with orotracheal intubation for surgery lasting more than 60 minutes at the visceral surgery unit of the Rouen University Hospital.
Person affiliated to a social security scheme
Person who has read and understood the newsletter and signed the consent form

Exclusion criteria

Minor patients or age> 80 years
History of Obstructive Sleep Apnea Syndrome
Chronic respiratory failure / History of chronic obstructive pulmonary disease
Surgery < 60 minutes
Use of methylene blue intraoperatively
Extubation finally performed in the operating room
orotracheal intubation difficult to induce general anesthesia
Suspected inhalation during orotracheal intubation
Pneumothorax per operative
Heart failure authenticated by trans thoracic ultrasound <50%
Neuromuscular pathologies (myasthenia gravis, myopathies)
Body mass index> 35
Emergency surgery
Patient with an ASA IV score (ie according to the definition of the American Society of Anesthesiology)
Major surgical complications (hemorrhagic shock)
Major anesthetic complications (anaphylactic shock, bronchospasm)
Pregnant or parturient or lactating woman or woman of childbearing age without proven contraception
Person deprived of their liberty by an administrative or judicial decision or person placed under the protection of justice / guardianship or curatorship