Interferential Electrical Stimulation and Vasodilatation in Healthy Individuals (InterM)

Hospital de Clinicas de Porto Alegre

Status: Completed

Conditions: Decreased Vascular Flow

Treatments: Device: Interferential; Device: Interferential Placebo

Study type: Observational

Funder types: Other

Identifiers

NCT01450371

11-0374

Details and patient eligibility

About

Interferential electrical stimulation (IES) increases local blood flow. It is not known whether increases in blood flow may be caused by inhibition of sympathetic activity, mediated by muscle metaboreflex activity. The purpose of this study was to evaluate the effect of IES on metaboreflex activation in healthy subjects.

Full description

The study sample consisted of 11 healthy young individuals. All subjects were non-smokers, non-obese and free of any signs or symptoms of disease, as revealed by medical history, physical examination and electrocardiogram at rest and during cardiopulmonary exercise testing. Exclusion criteria were pregnancy, breast-feeding, alcohol or drug abuse, and any medication with potential effects on cardiovascular variables. Subjects were asked not to drink caffeine-containing drinks or exercise for at least 12 and 48 hours, respectively, before the experimental protocols.

Enrollment: 11 patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Subjects are non-smokers
• non-obese
• and free of any signs or symptoms of disease

Exclusion criteria

• Pregnancy
• breast-feeding
• alcohol or drug abuse
• medication with potential effects on cardiovascular variables

Trial design

11 participants in 2 patient groups

Interferential

Description:

The individuals are treated acutely with interferential electrical stimulation (IES) during 30 min, providing a continuous flow of symmetrical rectangular interferential current biphasic pulses using bipolar electrodes with two channels and a slope of 1/5/1. The fixed current is adjusted to 4000 Hz, with the current AMF at 100 Hz and an AMF variation of 25 Hz (25% of AMF).

Treatment:

Device: Interferential

Placebo

Description:

The same instructions and electrode positions were provided to the placebo, although the equipment did not provide any stimulation current

Treatment:

Device: Interferential Placebo