Interleukin-4 in Pityriasis Lichenoides Chronica

Cairo University (CU)

Status: Not yet enrolling

Conditions: Pityriasis Lichenoides

Treatments: Procedure: skin biopsy and serum sample

Study type: Interventional

Funder types: Other

Identifiers

NCT06889506

Dermatology 20

Details and patient eligibility

About

assessment of the level of interleukin 4 (IL-4) in the lesional skin and serum of PLC patients and compare its level with healthy controls.

Full description

measuring the level of Interleukin 4 in lesional skin and it's serum level using ELIZA in patients with Pityriasis lichenoides chronica and comparing the levels with healthy controls levels

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with pityriasis lichenoides Chronica (PLC): either with the classical presentation papular or hypo-pigmented macules and patches that proved histopathologically to be PLC.
• Both genders
• Age group ≥ 8 years

Exclusion criteria

• Patients with other skin diseases
• Patient received treatment for PLC within period less than three months
• Pregnant patients
• Lactating patients

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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50 participants in 2 patient groups

PLC patients

Active Comparator group

Description:

one skin biopsy (lesional) and serum sample will be taken from every patient

Treatment:

Procedure: skin biopsy and serum sample

healthy controls

Experimental group

Description:

a skin biopsy and serum sample will be taken from each control sample

Treatment:

Procedure: skin biopsy and serum sample