Interleukin (IL)-13 as a Marker in Pediatrics Asthma

Rush

Status: Completed

Conditions: Asthma

Study type: Observational

Funder types: Other

Identifiers

NCT00968305

L06121901

Details and patient eligibility

About

Asthma is a very common childhood chronic illness and is generally more severe in African Americans. The investigators attempted to determine whether a specific immune marker is associated with lung function and asthma severity.

Full description

This study examined the relationship between Interleukin (IL)-13 from phytohemagglutinin-activated polymorphonuclear blood cells and asthma severity, lung function (measured as FEV1%), and total serum IgE levels in African American children with clinically diagnosed asthma

Enrollment: 19 patients

Sex: All

Ages: 8 to 15 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• African-American race, born in the U.S.
• Age 8-15 years
• Clinical diagnosis of asthma
• Subject is able to understand and follow verbal instructions in English

Exclusion criteria

• Asthma exacerbation in the 4 weeks preceding the research visit
• Oral/IV steroid use in the 4 weeks preceding the research visit
• Upper or lower respiratory tract infection in the 4 weeks preceding the research visit
• Antibiotic use in the 4 weeks preceding the research visit
• Use of a short-acting bronchodilator during the 6 hours prior to spirometry (lung function testing)
• Use of a long-acting bronchodilator during the 12 hours prior to spirometry (lung function testing)

Trial design

19 participants in 1 patient group

Children with asthma

Description:

African American children with clinically diagnosed stable asthma