Intermedius Genicular Nerve in the Treatment of Patients With Chondromalacia Patella

Gaziler Physical Medicine and Rehabilitation Education and Research Hospital

Status: Unknown

Conditions: Chondromalacia Patellae

Treatments: Procedure: radiofrequency; Procedure: control; Drug: 2% lidocaine

Study type: Interventional

Funder types: Other

Identifiers

NCT05096520

19

Details and patient eligibility

About

Radiofrequency application is a treatment method that temporarily prevents the transmission of pain in the nerve where the application is made through the heat emitted by radio waves.Partial inhibition of the functions of the nerves carrying the joint pain sensation with this method is the basis of the treatment.The intermedius genicular nerve carries the sensation of subpatellar pain due to chondromalacia.In this study,investigators aim is to investigate the effect of radiofrequency neurotomy applied to the intermedius genicular nerve, which receives the sensation of the patella, on pain and knee function in patients with a diagnosis of chondromalacia patella who have anterior knee pain that does not resolve despite conservative treatment, under the guidance of ultrasonography.

Full description

The study was designed as prospective, randomized, controlled trial. 46 people who met the inclusion criteria were randomized into two groups of 23 people. The first group will be designated as Nerve blockage group and nerve blocking program will be applied to these patients. Patients in the second group will be designated as the Radiofrequency group and radiofrequency ablation after the blockade program will be applied in accordance with the radiofrequency ablation protocol.Participants were evaluated with Visual Analogue Scale (VAS), Patello Femoral Pain Severity Scale (PFPSS), Kuala's Patellofemoral Scoring System (KPSS).

Enrollment: 46 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male/female aged >18 years
• Diagnosis of chondromalacia patella after physical examination and MR imaging
• Those whose symptoms persist for >3 months
• Participating in the study voluntarily

Exclusion criteria

• Pregnant patients
• History of previous knee surgery
• To have received physical therapy from the knee area in the last 6 months
• Previous RF treatment or any therapeutic injection of the knee such as steroid, hyaluronic acid within 3 months
• Those with pain radiating from the waist or hip
• Patients with neuropathic pain
• History of tumor, infectious, psychiatric disease, bleeding diathesis
• History of knee trauma in the last 6 months
• Those with systemic diseases such as hepatitis, coagulopathy
• Patients with BMI >40
• Finding a leg length difference

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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46 participants in 2 patient groups

radiofrequency group

Active Comparator group

Description:

the radiofrequency needle will be advanced percutaneously towards the intermedius genicular nerve on the periosteum of the distal femoral shaft region until bone contact is achieved. In addition to imaging the nerve with ultrasound, sensory stimulation at 50 Hz frequency will be applied with a threshold value less than 0.6 V in order to determine its position more accurately. In order to prevent the inactivation of the motor nerves, the relevant nerve will be tested for the absence of fasciculation in the region of the lower extremity compatible with the application with the stimulation with a frequency of 2.0 V and 2 Hz. Before the activation of the radiofrequency generator, an injection of 1 ml of 2% lidocaine will be made, then the radiofrequency electrode will be added to the needle and the temperature level at the tip of the electrode will be increased to 80 degrees for 2 minutes, the procedure will be performed for each genicular nerve.

Treatment:

Drug: 2% lidocaine

Procedure: radiofrequency

control group

Active Comparator group

Description:

The intermedius genicular nerve will be found under US guidance and the genicular nerve will be blocked by injecting 1 ml of 2% lidocaine.

Treatment:

Drug: 2% lidocaine

Procedure: control