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Intermittent Cold Blood vs Crystalloid Cardioplegia in Aortic Valve Surgery

University of Oslo (UIO) logo

University of Oslo (UIO)

Status

Completed

Conditions

Coronary Artery Disease
Aortic Valve Disease

Treatments

Procedure: Myocardial protection techniques

Study type

Interventional

Funder types

Other

Identifiers

Details and patient eligibility

About

Controversies still exists concerning the overall clinical effects of blood-based vs. crystalloid- based cardioplegic solution for myocardial protection during cardiac arrest. Both techniques are used world-wide. No larger prospectively randomized studies comparing the two methods have been reported. The aim of this study is to collect a large number of clinical data to create a proper basis for evaluation of the two techniques.

Full description

All patients admitted for aortic valve replacement with or without concomitant CABG and operated by E.Ø. or G.T. are included in the study. All preoperative, operative and postoperative data are prospectively recorded, focusing on clinical outcome parameters

Enrollment

350 estimated patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion and exclusion criteria

Aortic valve replacement

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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