Intermittent Theta Burst Stimulation and Repetitive Transcranial Magnetic Stimulation Combined With Robotic Rehabilitation on Ambulation in Spinal Cord Injury Patients

Gaziler Physical Medicine and Rehabilitation Education and Research Hospital

Status: Completed

Conditions: Spinal Cord Injuries

Treatments: Device: Transcranial Magnetic Stimulation

Study type: Interventional

Funder types: Other

Identifiers

NCT06248476

E2-23-5440

Details and patient eligibility

About

Comparison of different types of transcranial magnetic stimulation techniques which are intermittent theta burst stimulation (iTBS) and high frequency repetitive transcranial magnetic stimulation (rTMS) in patients with spinal cord injury

Full description

iTBS lasts shorter than rTMS so that this technique comfortable than rTMS for both patients and also physicians. Aim of this study is to compare effectiveness of this techniques. If results are same, iTBS can be used instead of rTMS.

Enrollment: 30 patients

Sex: All

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Incomplete spinal cord injury (ASIA C and D)
• 12 months after spinal cord injury
• At least 10 meters walking independent or with canadian, walker or walking stick
• Put signature to approved form

Exclusion criteria

• Epileptic seizure
• Pacemaker
• Pregnancy
• Neurological disease different from spinal cord injury
• Metalic implant in brain or scalp
• Brain surgery
• Orthopedic problem in lower extremity
• Malignity

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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30 participants in 3 patient groups

iTBS + robotic rehabilitation

Active Comparator group

Description:

iTBS combined with robotic rehabilitation and conservative treatment applied to patients with chronic incomplete spinal cord injury

Treatment:

Device: Transcranial Magnetic Stimulation

rTMS + robotic rehabilitation

Active Comparator group

Description:

rTMS combined with robotic rehabilitation and conservative treatment applied to patients with chronic incomplete spinal cord injury

Treatment:

Device: Transcranial Magnetic Stimulation

sham iTBS + robotic rehabilitation

Sham Comparator group

Description:

Sham iTBS combined with robotic rehabilitation and conservative treatment applied to patients with chronic incomplete spinal cord injury

Treatment:

Device: Transcranial Magnetic Stimulation