International Headache Registry Study (IHRS)

Zhejiang University

Status: Enrolling

Conditions: Fibromyalgia; Vertigo; Vestibular Migraine; Tension-Type Headache; Headache Disorders, Secondary; Migraine; Headache Disorders, Primary

Study type: Observational

Funder types: Other

Identifiers

NCT05418218

20220430

Details and patient eligibility

About

In the International Headache and Vertigo Registration Study, patients aged 4-99 years with headache (primary headache and secondary headache such as migraine and tension type headache), vertigo (vertigo diseases such as vestibular migraine) and chronic pain (fibromyalgia and other diseases) were collected. The biomarkers, imaging features, right-to-left shunt of the heart (lung), genetic characteristics, treatment, and outcome (in relation to other diseases) of headache-related diseases were studied, and long-term follow-up was planned.

Full description

1. Research contents:

   In the International Headache and Vertigo Registration Study, patients aged 4-99 years with headache (primary headache and secondary headache such as migraine and tension type headache), vertigo (vertigo diseases such as vestibular migraine) and chronic pain (fibromyalgia and other diseases) were collected. The biomarkers, imaging features, right-to-left shunt of the heart (lung), genetic characteristics, treatment, and outcome (in relation to other diseases) of headache-related diseases were studied, and long-term follow-up was planned.

2. Research target:

We study biomarkers, imaging features, right-to-left shunt of heart (lung), genetic features, real-world treatment studies, and outcomes (in relation to other diseases) for headache and vertigo related diseases.

Enrollment: 200,000 estimated patients

Sex: All

Ages: 4 to 99 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

The following are requirements for entry into the study:

1. Written informed consent and participant privacy information (eg, Written Authorization for Use and Release of Health and Research Study Information) obtained from the participant prior to initiation of any study-specific procedures.
2. Male or female participants ages 4 to 99 years, inclusive, at Visit 1.
3. Headache patients meeting the diagnostic criteria for ICHD-3, including primary headaches such as migraine and tension tension-type headaches, secondary headaches, and patients who meet the headache diagnosis in the ICHD-3 appendix (including vestibular migraine).

Exclusion criteria

1. Patients who were unable to complete scales such as headache diary.
2. Patients denied or unable to be admitted for long-term follow-up.

Trial design

200,000 participants in 5 patient groups

Migraine

Description:

Patients with migraine (including vestibular migraine), including all types of migraine as defined by ICHD-3.

Other Primary Headache Disorders

Description:

Patients with other primary headache disorders (excluding migraine), including all types of other primary headache disorders (such as Tension-Type Headache, Cluster Headache) as defined by ICHD-3.

Vertigo

Description:

Patients with other vertigo disorders (excluding vestibular migraine).

Secondary Headache Disorders

Description:

Patients with secondary headache disorders as defined by ICHD-3.

Normal control

Description:

Normal people do not have headache and vertigo.