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International Multicenter Mycotic Aneurysm Aorto-iliac Study (MAAI)

I

Institute of Hospitalization and Scientific Care (IRCCS)

Status

Enrolling

Conditions

Mycotic Aneurysm
Aortic Diseases

Treatments

Procedure: Mycotic aortic-iliac aneurysms and in situ reconstruction

Study type

Observational

Funder types

Other

Identifiers

Details and patient eligibility

About

The term mycotic aneurysm (MA) is commonly used to describe all infected aneurysms. Although MAs are believed to occur uncommonly, the true incidence is difficult to determine and is probably underestimated since MAs can be asymptomatic and are diagnosed only at autopsy. In an autoptic study, mycotic aortic aneurysms (MAAs) were reported in 3.3% of all detected aneurysms. The incidence of infected aneurysms of the aorta and iliac arteries ranges from 0.6% to 1.3%.

A recent literature review of the management of MAAs showed that therapeutic strategies are multiple, including open surgical repair (OSR) in the majority of cases, endovascular aortic repair (EVAR), which increased over the last decade, and medical treatment alone for patients unfit for any aortic repair in a very limited part. Following the unfavorable prognosis towards rupture and since the medical treatment alone in mycotic aneurysms has shown mortality of almost 100%, surgical treatment is generally the preferred option.

Surgical treatment includes both open and endovascular surgery. The latter is less invasive than conventional surgery but does not involve resection of the infected tissue and is therefore associated with an increased risk of sepsis and prosthesis infection. The gold standard is still open surgery, including extra-anatomic reconstruction and in situ repair, with different type of vascular graft.

This is a multicenter retrospective observational study. It will examine all patients undergoing surgical treatment of mycotic aortic-iliac aneurysms and in situ reconstruction at the participating centers.

Enrollment

40 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • primary mycotic aorto-iliac aneurysm who underwent in situ repair

Exclusion criteria

  • patient with vascular graft infections;
  • patient with secondary aorto-enteric fistula.

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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