International Registry of Congenital Portosystemic Shunt (IRCPSS)

Prof. Valérie Mc Lin

Status: Invitation-only

Conditions: Congenital Porto-Systemic Shunt (CPSS)

Treatments: Procedure: Shunt Closure

Study type: Observational

Funder types: Other

Identifiers

NCT06041906

2018-00413

Details and patient eligibility

About

Congenital Portosystemic Shunt (CPSS) is a rare condition important by the multiplicity and severity of associated complications.

CPSS is venous anomaly in which blood coming from the intestines only partially passes through the liver.

This leads to the accumulation of potentially toxic factors that cause systemic effects.

Complications vary among the individuals, and currently, it is challenging to predict which individuals will develop severe complications.

The IRCPSS registry is established with the aim of centralizing detailed clinical follow-up and biological information from participants around the world who suffer from Congenital Portosystemic Shunt (CPSS). A multidisciplinary consortium of experts is collaborating to enhance our understanding of the prevalence, natural history, individual risks, and physiopathology of the disease through the IRCPSS registry.

Enrollment: 500 estimated patients

Sex: All

Ages: 1+ day old

Volunteers: No Healthy Volunteers

Inclusion criteria

Individual with CPSS

Exclusion criteria

Secondary shunt without evidence of congenital shunt

Trial design

500 participants in 1 patient group

Neonate, Children, Adult with CPSS

Treatment:

Procedure: Shunt Closure