Internet-based CBIT for Children With Chronic Tics

Tel Aviv Medical Center (TAMC)

Status: Unknown

Conditions: Chronic Tic Disorder; Tourette Syndrome in Adolescence; Tourette Syndrome in Children

Treatments: Behavioral: ICBIT; Behavioral: waiting list

Study type: Interventional

Funder types: Other

Identifiers

NCT04087616

TelAvivSMO

Details and patient eligibility

About

To evaluate the effect and acceptability of an Internet-based comprehensive behavioral intervention for tics (ICBIT) in a sample of children and adolescents with Tic disorders. children and adolescents (aged 8-17 years) with Tourette Syndrome (TS) or Chronic Tic Disorder (CTD) and their parents will be randomly assigned to receive either an Internet-based ICBIT or wait-list (WL).

Full description

To evaluate the effect and acceptability of an Internet-based comprehensive behavioral intervention for tics (ICBIT) in a sample of children and adolescents with Tic disorders, children and adolescents (aged 8-17 years) with Tourette Syndrome (TS) or Chronic Tic Disorder (CTD) and their parents will be randomly assigned to receive either an Internet-based ICBIT or wait-list (WL) condition in a cross over design.

Participants will be randomized to ICBIT, or to wait list, and half will cross over from wait list to ICBT. Two blind independent clinical evaluators will rate tic severity and comorbidity. The primary outcome measure is the Yale Global Tic Severity Scale (YGTSS). Assessments will be performed at baseline, post-ICBT or post wait list, 3-months and 6-months (post-treatment for those originally assigned to ICBT) and post-ICBT, 3-months and 6-months (post-treatment for those originally assigned to wait list condition). All assessments were conducted by 2 PhD level independent child psychologists.

Enrollment: 40 estimated patients

Sex: All

Ages: 8 to 17 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of Tourette Syndrome or Chronic Tic Disorder.
• Yale Global Tic Severity Scale tic severity score ≥14.

Exclusion criteria

• Change in psychotropic medication regimen during the past 6 weeks.
• Current diagnosis of substance abuse/dependence.
• Lifetime diagnosis of pervasive developmental disorder, mania or psychosis.
• Previous sessions of CBIT.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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40 participants in 2 patient groups, including a placebo group

CBIT

Experimental group

Description:

ICBIT. Intervention delivered through an internet platform called Managing children's' tics (www.cbteamathome.co.il), based on CBIT protocol (Woods et al., 2008) adapted to an online parent-guided self-help format.

Treatment:

Behavioral: ICBIT

Waiting List

Placebo Comparator group

Description:

Participants initially assigned to the wait list receive no psychosocial intervention for 9 weeks. Following post-WL assessment, all participants receive ICBIT.

Treatment:

Behavioral: waiting list