Internet-based Multidisciplinary Rehabilitation for Longterm COVID-19 Syndrome

Danderyd Hospital

Status: Unknown

Conditions: Long COVID-19

Treatments: Behavioral: Multidisciplinary Rehabilitation

Study type: Interventional

Funder types: Other

Identifiers

NCT04961333

Danderyd University Hospital

Details and patient eligibility

About

Internet-based multidisciplinary interventions will be offered to participants suffering from longterm COVID-19 syndrome. Data will be collected by internet platform at Karolinska Institutet (BASS) before, after rehabilitation and at follow-up after 6 months. Both self-scored questionnaires and physical tests performed at home will be collected to understand the symptomatology, functioning and activity level. Rehabilitation during 8 weeks period will be given in groups as face-to-group, pre-recorded film sessions and by individual approach, the participants will use ExorLive app for physical activity.

Full description

This randomised study aimed to understand if multidisciplinary internet-based interventions performed in group and individually are applicable for participants suffering from longterm COVID-19 syndrome. Data will be collected by internet platform at Karolinska Institutet (BASS) before, after rehabilitation and at follow-up after 6 months. Both self-scored questionnaires and physical tests performed at home will be collected to understand the symptomatology, functioning and activity level. Rehabilitation during 8 weeks period will be given in groups as face-to-group, pre-recorded film sessions and by individual approach, the participants will use ExorLive app for physical activity.

The participants will be randomised for treatment and waiting lists using a website random.org. Waiting list will be offered rehabilitation interventions after at least 8 weeks period of waiting to exclude a spontaneous improvement or worsening of symptoms. To understand the impact of rehabilitation on work capacity and employment/economic supply, the data from Social Insurance databas will be obtained 2021 year before and upp to 2 years after the intervention. To understand the impact of rehabilitation on sickness-leave, the data from National Insurance Agency will be obtained for 2021 and 2022.

Enrollment: 200 estimated patients

Sex: All

Ages: 18 to 67 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• confirmed COVID-19 infection
• post-infection symptoms lasting longer than 3-6 months
• clinically stable persons regarding symtoms or other co-morbidities
• ability to participate in internet-based rehabilitation in group in Swedish.

Exclusion criteria

• uncertainty regarding covid-19 infection or co-morbidities started or exacerbated during the same time
• alcohol and drug abuse
• untreated psychiatric and somatic co-morbidities
• undergoing medical or psychotherapeutic treatment or rehabilitation which can interact with rehabilitation outcomes.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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200 participants in 2 patient groups

Rehabilitation group

Experimental group

Description:

Rehabilitation group will be provided multidisciplinary interventions online and individually by ExorLive app. The screening with self-scored questionnaires and physical tests will be performed before and after 8 weeks rehabilitation.

Treatment:

Behavioral: Multidisciplinary Rehabilitation

Waiting list controls

No Intervention group

Description:

Passive waiting list or control group, which will be offered to participate in rehabilitation after at least 8 weeks of waiting time. The group will fulfil screening twice, following the time schedule of intervention group. When invited to rehabilitation a new screening will be asked to be completed if the waiting time after the last screening will be longer than 2 weeks.