Interpersonal Brain Function in Opioid Use

University of California San Diego

Status: Enrolling

Conditions: People Who Use Opioids/People With Opioid Use Disorder (OUD)

Treatments: Behavioral: Psychoeducation; Behavioral: Meditation

Study type: Interventional

Funder types: Other

Identifiers

NCT07386769

813632

Details and patient eligibility

About

The purpose of this study is to assess dyadic physiological coherence and subjective empathic attunement during meditation practices and their association with opioid-related outcomes.

Enrollment: 60 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Persons, aged 18 or older
2. Current near daily use of prescribed or illicit opioid agonists or mixed opioid agonist-antagonists for ≥90 days
3. Must be able to speak and understand English

Exclusion criteria

1. Cognitive Impairment that would preclude participation in the research protocol
2. Active suicidal intent or psychosis

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups

Meditation

Experimental group

Description:

20 minutes of guided meditation during the laboratory session involving mindfulness of breathing and lovingkindness practice.

Treatment:

Behavioral: Meditation

Psychoeducation

Active Comparator group

Description:

Psychoeducation about opioid neuropharmacology.

Treatment:

Behavioral: Psychoeducation