Interpersonal Psychotherapy in Youth With Severe Mood Dysregulation-Pilot

Johns Hopkins University

Status: Completed

Conditions: Severe Mood Dysregulation

Treatments: Behavioral: Interpersonal Psychotherapy for youth with SMD (IPT-SMD)

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT01591564

NA_00046454

K23MH090246 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The purpose of this study is to determine the feasibility and acceptability of an utilizing an adapted form (IPT-SMD)of a psychosocial intervention, Interpersonal Psychotherapy for Depressed Adolescents, for youth with severe mood dysregulation (SMD).

The investigators hypothesize that retention rates will be >80%,satisfaction scores will average 6 (high) on a 7 point satisfaction scale, and that youth who receive the IPT-SMD intervention will have overall improvement in SMD symptoms.

Enrollment: 3 patients

Sex: All

Ages: 13 to 17 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Male and female subjects, ages 13 to 17 years, who meet criteria for severe mood dysregulation as defined by NIMH criteria.
• Subject has an estimated IQ >70 on the Kaufman Brief Intelligence Test (KBIT-2)
• Subjects will have continuously resided with a legal guardian who has known the adolescent well for at least one year before study entry and is legally able to sign the consent form.
• Participants must be on the same dose of any prescribed medication for 4 weeks prior to randomization.
• Children's Global Assessment Scale (CGAS) ≤ 60

Exclusion criteria

• Subject poses a significant risk for dangerousness to self or others. Risk will be determined by clinical history, clinical diagnostic interview and KSADS-PL interview of parent and patient by clinician.
• Subject suffers from a concomitant medical or psychiatric co-morbidity that makes this study protocol inadvisable (either the treatment is contraindicated or the disorder is not the primary focus of treatment).
• Subject meets DSM-IV criteria for current alcohol or substance dependence or current use (defined as the past 4 weeks).
• Pregnant females.
• Primary caretaker does not speak English

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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3 participants in 1 patient group

therapy

Other group

Description:

All participants will receive the intervention.

Treatment:

Behavioral: Interpersonal Psychotherapy for youth with SMD (IPT-SMD)