Interplay Between Oxytocin and Cortisol During Stress in Borderline Personality Disorder (OXT-CORT-BPD)

University of Geneva, Switzerland

Status: Completed

Conditions: Borderline Personality Disorder; Oxytocin

Treatments: Other: stress test

Study type: Observational

Funder types: Other

Identifiers

NCT05357521

2002-00067

Details and patient eligibility

About

This study aims to determine the feasibility and preliminary data on the interaction between oxytocin and cortisol during stress in borderline personnality disorder.

Full description

The investigators will recruit 50 female patients with borderline personnality disorder and 50 controls with no psychiatric diagnosis, aged between 18 and 25 years old.

salivary cortisol daily curve ( 6 measures during the day) will be measured in participant's naturalistic environnement, together with salivary oxytocin. In addition, salivary oxytocin and cortisol will be measured during a psychosocial stress task and recovery.

Enrollment: 100 patients

Sex: Female

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Borderline personality disorder-DSM V

Exclusion criteria

• Schizophrenia

Trial design

100 participants in 2 patient groups

Borderline personality disorder

Description:

female patients between 18 and 25 years old meeting DSM V criteria for borderline personality disorder

Treatment:

Other: stress test

Control

Description:

female participants between 18 and 25 years old, with no psychiatric history, not meeting criteria for borderline personality disorder

Treatment:

Other: stress test