Interrupting Prolonged Sitting With Periodic Interval Exercise: Effect on Postprandial Lipemia

The University of Texas System (UT)

Status: Unknown

Conditions: Hypertriglyceridemia; Sedentary Behavior

Treatments: Behavioral: Interrupting Prolonged Sitting with Periodic Interval Exercise: Effect on Postprandial Lipemia

Study type: Interventional

Funder types: Other

Identifiers

NCT04241081

2019-10-0091

Details and patient eligibility

About

Investigating the effects of interrupting various lengths of prolonged sitting with bike sprints on post prandial lipemia the next day. We will conduct three trials, one control, one with two-hour sitting intervals (total of 4 bouts of bike sprints) and one with 6-hour sitting intervals I total of two bouts of bike sprints). A milkshake high fat tolerance test will be conducted the next day and whole body fat oxidation as well as triglyceride area under the curve will be measured every hour for the duration of the 6-hour test.

Enrollment: 15 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Inactive or recreational healthy adults aged 18-65 years old.

Exclusion criteria

• Lactose intolerance, cardiovascular or metabolic diagnoses, medications for cardiovascular or metabolic diagnoses, orthopedic issues barring cycling.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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15 participants in 3 patient groups

Control group-no exercise

No Intervention group

Description:

A no-exercise control. Must maintain \<4,500 steps per day for 3 consecutive days followed by a high fat tolerance test on day 4.

Exercise intervention 1

Experimental group

Description:

Two consecutive days of \<4,500 steps per day followed by an intervention day on day 3. Intervention day consists of interrupting 8-hour sit with bike sprint protocol every 2 hours. Participants must aim to maintain \<2,500 steps on intervention day. A high fat tolerance test will be performed the following day on day 4.

Treatment:

Behavioral: Interrupting Prolonged Sitting with Periodic Interval Exercise: Effect on Postprandial Lipemia

Exercise intervention 2

Experimental group

Description:

Two consecutive days of \<4,500 steps per day followed by an intervention day. Intervention day consists of interrupting 8-hour sit with bike sprint protocol every 6 hours. Participants must aim to maintain \<2,500 steps on intervention day. A high fat tolerance test will be performed the following day on day 4.

Treatment:

Behavioral: Interrupting Prolonged Sitting with Periodic Interval Exercise: Effect on Postprandial Lipemia