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Interrupting Prolonged Sitting With Periodic Interval Exercise: Effect on Postprandial Lipemia

The University of Texas System (UT) logo

The University of Texas System (UT)

Status

Unknown

Conditions

Hypertriglyceridemia
Sedentary Behavior

Treatments

Behavioral: Interrupting Prolonged Sitting with Periodic Interval Exercise: Effect on Postprandial Lipemia

Study type

Interventional

Funder types

Other

Identifiers

NCT04241081
2019-10-0091

Details and patient eligibility

About

Investigating the effects of interrupting various lengths of prolonged sitting with bike sprints on post prandial lipemia the next day. We will conduct three trials, one control, one with two-hour sitting intervals (total of 4 bouts of bike sprints) and one with 6-hour sitting intervals I total of two bouts of bike sprints). A milkshake high fat tolerance test will be conducted the next day and whole body fat oxidation as well as triglyceride area under the curve will be measured every hour for the duration of the 6-hour test.

Enrollment

15 estimated patients

Sex

All

Ages

18 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Inactive or recreational healthy adults aged 18-65 years old.

Exclusion criteria

  • Lactose intolerance, cardiovascular or metabolic diagnoses, medications for cardiovascular or metabolic diagnoses, orthopedic issues barring cycling.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

None (Open label)

15 participants in 3 patient groups

Control group-no exercise
No Intervention group
Description:
A no-exercise control. Must maintain \<4,500 steps per day for 3 consecutive days followed by a high fat tolerance test on day 4.
Exercise intervention 1
Experimental group
Description:
Two consecutive days of \<4,500 steps per day followed by an intervention day on day 3. Intervention day consists of interrupting 8-hour sit with bike sprint protocol every 2 hours. Participants must aim to maintain \<2,500 steps on intervention day. A high fat tolerance test will be performed the following day on day 4.
Treatment:
Behavioral: Interrupting Prolonged Sitting with Periodic Interval Exercise: Effect on Postprandial Lipemia
Exercise intervention 2
Experimental group
Description:
Two consecutive days of \<4,500 steps per day followed by an intervention day. Intervention day consists of interrupting 8-hour sit with bike sprint protocol every 6 hours. Participants must aim to maintain \<2,500 steps on intervention day. A high fat tolerance test will be performed the following day on day 4.
Treatment:
Behavioral: Interrupting Prolonged Sitting with Periodic Interval Exercise: Effect on Postprandial Lipemia

Trial contacts and locations

1

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Central trial contact

Edward Coyle, PhD; Rebecca braden, BS

Data sourced from clinicaltrials.gov

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