Interruption of Dorsal Visual Stream Using TMS

Sheba Medical Center

Status: Completed

Conditions: Healthy

Treatments: Device: No TMS intervention; Device: TMS over the PO3 EEG site; Device: TMS over the vertex

Study type: Interventional

Funder types: Other

Identifiers

NCT00418652

SHEBA-06-4252-RA-CTIL

Details and patient eligibility

About

Trans Cranial Magnetic Stimulation (TMS) over dorsal visual system will disturb the ability to identify objects with decreased level of fragmentation

Full description

The participants performed two tasks under three different TMS conditions: no TMS, 10Hz TMS for over the dorsal stream (PO3 EEG site) or over the vertex.

First they performed a perceptual closure task which asked them to identify an object in a series of six progressively less degraded pictures.

Then, they also performed a control task previously shown not to be mediated by the LOC and not to be impaired in schizophrenia: The perception of illusory contours.

Enrollment: 12 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Normal controls

Exclusion criteria

• neurological, ophthalmological or psychiatric problems
• family history of schizophrenia
• left handed

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Single Blind

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12 participants in 3 patient groups

No TMS stimulation

No Intervention group

Description:

The patients performed 2 tasks: a study and a control assignments with no TMS stimulation.

Treatment:

Device: No TMS intervention

TMS over the dorsal stream

Experimental group

Description:

The patients performed 2 tasks: a study and a control assignments under TMS stimulation over the dorsal stream area (PO3 EEG site).

Treatment:

Device: TMS over the PO3 EEG site

TMS over the vertex

Sham Comparator group

Description:

The patients performed 2 tasks: a study and a control assignments under TMS stimulation over the vertex area.

Treatment:

Device: TMS over the vertex