Intervention Comparative Effectiveness for Adult Cognitive Training (ICE-ACT)

Florida State University

Status: Completed

Conditions: Cognitive Aging

Treatments: Behavioral: Active Control; Behavioral: IADL Training; Behavioral: BrainHQ; Behavioral: Rise of Nations

Study type: Interventional

Funder types: Other

Identifiers

NCT03141281

2017.20622

Details and patient eligibility

About

The study will compare the effect of broad and directed (narrow) technology-based training on basic perceptual and cognitive abilities in older adults and on the performance of simulated tasks of daily living including driving and fraud avoidance.

Full description

Participants will be randomly assigned to four training conditions: broad training using either 1) Posit Science's web-based "BrainHQ" or 2) the video game Rise of Nations, or to directed training for 3) Instrumental Activities of Daily Living (IADL) training on both driving, American Association of Retired Persons (AARP)'s web-based older driver training program, and training for fraud avoidance, a web-based tutorial on finance and fraud, or 4) to an active control condition of puzzle solving. Training will take approximately 15-20 hr for each treatment condition. Before training begins, participants will take baseline ability tests of perception, attention, memory, and cognition, activities of daily living, as well as a driving simulator test for hazard perception, and a financial fraud recognition test. They will be tested again on these measures following training completion, and at a one-year follow-up from training completion.

Enrollment: 238 patients

Sex: All

Ages: 65+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age 65 years and above
• Plans to stay in the Tallahassee, Leon County area for the next year
• Valid driver's license and drives at least once a month
• Adequate cognitive ability assessed via telephone interview using the Wechsler Memory Scale III with story A score >6 or story B score >4.

Exclusion criteria

• Terminal illness with life expectancy less than 12 months
• Reports or exhibits a disabling visual condition assessed as the inability to read printed material
• Reports or exhibits a disabling speech hearing and comprehension condition assessed by inability to hear and comprehend the screener's instructions
• Reports or exhibits a disabling speech production condition assessed as the inability to respond with comprehensible English speech to the screener's queries
• Reports or exhibits a disabling psychomotor condition assessed as the inability to use a keyboard and pointing device
• Has completed the AARP driver training course
• Has played the Rise of Nations video game
• Has trained with Posit Science's "BrainHQ"
• Has trained on the Mind Frontiers video game.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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238 participants in 4 patient groups

BrainHQ

Experimental group

Description:

Participants will be provided with a laptop computer and enrolled in a commercial web-based cognitive training program, BrainHQ, trained on how to access it, and instructed to complete a fixed number of sessions in 20 hours.

Treatment:

Behavioral: BrainHQ

Rise of Nations

Experimental group

Description:

Participants will be provided with a laptop computer with the Rise of Nations video game, be trained in game play, and instructed to play the game for 20 hours

Treatment:

Behavioral: Rise of Nations

IADL training

Experimental group

Description:

Participants will be enrolled in American Association of Retired Persons' web-based driver training course, trained on how to access it, and asked to complete the course, estimated to take approximately 6-8 hours. They will also be provided with web-based access to a finance and fraud avoidance training tutorial, instructed on how to access it, and be asked to complete the course, estimated to take approximately 5-7 hours. The two courses combined are estimated to take about 15 hours.

Treatment:

Behavioral: IADL Training

Active Control

Active Comparator group

Description:

Participants will be provided with a laptop computer and asked to complete 20 hr of training with Sudoku, crossword puzzles, and word search

Treatment:

Behavioral: Active Control