Intervention of Air Pollution and Acute Coronary Syndrome

Peking University

Status: Unknown

Conditions: Acute Coronary Syndrome

Treatments: Device: mask

Study type: Interventional

Funder types: Other

Identifiers

NCT04126434

WeiHuang19

Details and patient eligibility

About

To determine the effect of intervention of ambient air pollution on acute coronary syndrome patients.

Full description

To investgate the effect of wearing facemasks to decreasing levels of exposure to ambient air on acute coronary syndrome patients.

Enrollment: 200 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Non-smoker of any type during past six months and living in a non-smoking household.
2. A diagnosis of myocardial infarction or unstable angina 7-90 days prior to signed informed consent.

Exclusion criteria

1. Unstable CV disorders including uncompensated heart failure, refractory angina, uncontrolled arrhythmias, critical valvular heart disease and severe hypertension.
2. A history of infection with human immunodeficiency virus.
3. History of malignancy including leukemia and lymphoma AND/OR any severe, life-threatening disease AND/OR history of drug abuse within the last 2 years.
4. Pregnancy or intent to get pregnant during the study period.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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200 participants in 2 patient groups

no masking

Sham Comparator group

Description:

not wearing facemask

Treatment:

Device: mask

masking

Active Comparator group

Description:

wearing facemask

Treatment:

Device: mask