INtervention Study In overweiGHT Patients With COPD (INSIGHT COPD)

Seattle Institute for Biomedical and Clinical Research

Status

Completed

Conditions

Weight Loss

Overweight

Life Style

Pulmonary Disease, Chronic Obstructive

Obesity

Treatments

Behavioral: Lifestyle Intervention

Study type

Interventional

Funder types

Other

Other U.S. Federal agency

Identifiers

NCT02634268

1U01HL128868

Details and patient eligibility

About

Symptoms of chronic obstructive pulmonary disease (COPD) and high body mass index (BMI) overlap. The investigators are trying to find out if a program proven to help people lose a modest amount of weight and increase their physical activity will improve COPD symptoms for those with a high BMI. The program uses a series of video sessions and self-study handouts focused on healthy eating and increasing physical activity, and encourages participants to monitor their weight, diet, and physical activity for one year. For those who want to, they will be able to work with a health coach to help meet weight and activity goals. We hope that the program will lead to improved exercise tolerance, body weight, dyspnea, generic health-related quality of life, and major cardiovascular risk factors (central obesity by waist circumference, Framingham Risk Score, and blood pressure) through 12 months of follow-up. To be in the study, participants will need to have COPD, high BMI, history of smoking, shortness of breath, and be at least 40 years old.

Enrollment

684 patients

Sex

All

Ages

40+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

40 years or older at time of eligibility screening;
Body mass index 25.0-44.9 kg/m2 (also see Figure 2);
Smoked more than 10 pack-years of cigarettes;
Shortness of breath;
COPD;
Able to participate fully in all study protocol/procedures including written informed consent process.

Exclusion criteria

Inability to speak, read, or understand English;
Active weight loss interventions;
Expected weight loss because of alternate explanations, such as from illness;
Unable to ambulate to weight scale for weight measurement;
Safety and/or adherence concerns due to severe physical or mental health issues or life expectancy <18 months;
Pregnant, lactating, or planning to become pregnant during the study period;
Participation in other intervention studies.