Trusted Messengers: Intervention to Promote COVID-19 Vaccination

University of Massachusetts, Worcester

Status: Completed

Conditions: Vaccination; Covid19

Treatments: Behavioral: Primary care text message outreach to unvaccinated patients and resources to support PCPs

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT04981392

H00023254

1R01MD016883-01 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The study aims to assess the impact of a multicomponent intervention to support Primary Care Provider (PCP) outreach to promote COVID-19 vaccination among vulnerable patients in and near Worcester, MA via a pragmatic, cluster randomized trial.

Full description

The goal of this study is to increase uptake of the COVID-19 vaccine among vulnerable populations through systematic primary care (PCP or clinic) text message outreach to unvaccinated patients, information provision via a study website, and resources to support PCPs.

The clinical trial will randomize 14 primary care clinics from three health systems in the Worcester, Massachusetts area to intervention or control. Eligible patients seen at a study clinic randomized to the intervention will receive a series of text messages from their PCP or primary care clinic recommending a study website as a trusted source of information about the COVID-19 vaccines and information on how and where to schedule a vaccination.

Providers at a study clinic randomized to the intervention will be provided resources to support their conversations with unvaccinated patients during the intervention. Resources will include access to the study website, factsheets to share with vaccine hesitant patients, prescription pads to be used to "prescribe' the website, and an electronic "smartphrase" that can automatically add information about the study website and how to schedule a COVID-19 vaccination to patients' After Visit Summary and/or clinic note.

Enrollment: 21,844 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients seen by a PCP at a participating clinic site within 3-years prior to study start
• Age > / = 18 years

Exclusion criteria

• Patients who have received at least one dose of a COVID-19 vaccine series prior to the start of the intervention
• Non-Massachusetts residents

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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21,844 participants in 2 patient groups

Intervention Arm

Experimental group

Description:

Primary care text message outreach to unvaccinated patients and resources to support PCPs

Treatment:

Behavioral: Primary care text message outreach to unvaccinated patients and resources to support PCPs

Control Arm

No Intervention group

Description:

Patients will receive usual care