Interventional Radiology for the Treatment of Symptomatic Portal Hypertension in Patients With Cavernous Transformation of Portal Vein

Sun Yat-sen University

Status: Unknown

Conditions: Hypertension, Portal; Portal Vein, Cavernous Transformation Of

Treatments: Device: 22-gauge chiba needle; Device: Balloon catheter; Device: 260-cm-long stiff shaft wire; Device: Covered stent; Device: Bare metal stent; Device: 6-French sheath; Procedure: Transhepatic portosystemic shunt

Study type: Interventional

Funder types: Other

Identifiers

NCT02504034

DORNO3HSYSU

Details and patient eligibility

About

To evaluate the values of portosystemic shunt and other interventional radiology approaches for treatment of symptomatic portal hypertension in patients with cavernous transformation of portal vein.

Enrollment: 150 estimated patients

Sex: All

Ages: 1 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients with portal hypertention who have enough image information to confirm cavernous transformation of portal vein.

Exclusion criteria

• Patients with known severe dysfunction of heart, lung, brain, kidney and other vital organs.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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150 participants in 1 patient group

Transhepatic portosystemic shunt

Experimental group

Description:

Patients with cavernous transformation of portal vein undergo transhepatic portalsystemic shunt and other interventional radiology treatment

Treatment:

Device: 6-French sheath

Procedure: Transhepatic portosystemic shunt

Device: 22-gauge chiba needle

Device: Covered stent

Device: Bare metal stent

Device: Balloon catheter

Device: 260-cm-long stiff shaft wire