Interventions for Postoperative Delirium: Biomarker-2 (IPOD-B2)

University of Wisconsin (UW)

Status: Completed

Conditions: Delirium

Treatments: Procedure: High Density-Electroencephalogram

Study type: Observational

Funder types: Other

Identifiers

NCT02926417

A530900 (Other Identifier)

2015-0960

SMPH/ANESTHESIOLOGY/ANESTHESIO (Other Identifier)

Protocol Version 4/20/2020 (Other Identifier)

Details and patient eligibility

About

The IPOD-B2 Study aims to understand the pathogenesis of postoperative delirium in patients undergoing major surgery. The investigators will identify then correlate soluble biomarkers in blood and cerebral spinal fluid with changes in High Density-Electroencephalogram.

Enrollment: 32 patients

Sex: All

Ages: 21+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Adult (>21 years old)
2. Patients scheduled for an elective open thoracoabdominal aortic aneurysm or TEVAR (thoracic endovascular aortic/aneurysm repair)
3. Requiring spinal drain for surgery that is predicted to stay in two or more days
4. Willing and able to provide informed consent

Exclusion criteria

1. Contraindication for spinal drain
2. Documented history of dementia
3. Unable to communicate with the research staff due to language barriers
4. Individuals who the PI determines are not appropriate for the study such as a history of appointment cancellations.
5. Pregnant or Nursing
6. Prisoners