Intestinal Fatty Acid Binding Protein in Very Low Birth Weight Infants With Meconium Obstruction

Seoul National University

Status: Completed

Conditions: Meconium Obstruction of Prematurity

Study type: Observational

Funder types: Other

Identifiers

NCT02864446

1208-071-422

Details and patient eligibility

About

Urinary intestinal fatty acid binding protein (i-FABP), a marker of intestinal mucosal cell damage, has recently been proposed as a clinically useful measure in the early detection of necrotizing enterocolitis (NEC). However, there are no data on urinary i-FABP in meconium obstruction of prematurity (MOP). This study aimed to evaluate urinary i-FABP in MOP patient as a marker for early detection.

Enrollment: 100 patients

Sex: All

Ages: Under 36 weeks old

Volunteers: No Healthy Volunteers

Inclusion criteria

• preterm infants weighing <1,250g

Exclusion criteria

• major congenital anomalies
• perinatal asphyxia (cord pH <7.0)