Intestinal Microbiota of Patients Hospitalized With Sars-CoV-2 (MICRODIGCOV)

Centre Hospitalier Universitaire de Nīmes

Status

Active, not recruiting

Conditions

COVID-19

Treatments

Other: Fecal sample

Study type

Observational

Funder types

Other

Identifiers

NCT05178238

NIMAO/2021-1/AS-01

Details and patient eligibility

About

The study investigators hypothesize that SARS-Cov2 infection alters the composition of the digestive microbiota and its functionality, resulting in changes in intestinal permeability and consequently in microbial digestive translocation. These changes may correlate with the magnitude of the SARS-CoV-2 viral load in the gastrointestinal tract and may have an impact on the clinical manifestations and evolvability of COVID-19.

Enrollment

15 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

patient hospitalized at in Nimes University hospital
Infection with SARS-CoV-2 confirmed by RT-PCR
The patient must have signed the consent form
The patient must be a member or beneficiary of a health insurance plan

Exclusion criteria

The subject is participating in an interventional study susceptible to modify the intestinal microbiota, or is in a period of exclusion determined by a previous study
It is impossible to give the subject informed information
The patient is under safeguard of justice or state guardianship
Patient with a chronic digestive pathology or having been operated in the previous year or having enteral nutrition or having had bariatric surgery
Patient is pregnant, parturient or breastfeeding