Intra-abdominal Hypertension in Critically Ill Patients

Western University, Canada

Status: Completed

Conditions: Abdominal Compartment Syndrome; Intra-Abdominal Hypertension

Treatments: Other: No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT02514135

WesternUCanada

Details and patient eligibility

About

The aim of the proposed study is to determine the incidence and prevalence of intra-abdominal hypertension and abdominal compartment syndrome in consecutive intensive care admissions using broad inclusion criteria.

Full description

Increased pressure within the abdominal cavity is particularly common in intensive care patients and has been shown to be an independent risk-factor for mortality in this patient population. The quoted rates of intra-abdominal hypertension of range anywhere from 20-60% are dependent on the population of patient studied. The prospective observational studies performed to date have been underpowered, used strict inclusion/exclusion criteria or were performed prior to consensus guidelines on the definition and measurement of intra-abdominal pressure and hypertension.

Enrollment: 286 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Foley catheter in-situ on admission

Exclusion criteria

• Contra-indication to bladder pressure measurement
• Home service asked that patient is not included
• Death within 24 priors of admission before bladder pressure measured
• No bladder pressure performed within 24 hours of admission
• Consent refused or unable to be obtained (lack of SDM, patient unable to provide)

Trial design

286 participants in 2 patient groups

Elevated Intra-abdominal Pressure

Description:

Patients with intra-abdominal pressure \> 12 mmHg at any time throughout admission

Treatment:

Other: No intervention

Normal Intra-abdominal Pressure

Description:

Patients with intra-abdominal pressure \< 12 mmHg throughout admission

Treatment:

Other: No intervention