Intra-Abdominal Pressure Effect on Intra-Abdominal Volume and Airway Pressures During Laparoscopy

La Fe University and Polytechnic Hospital

Status: Completed

Conditions: Intra Abdominal Pressure; Pneumoperitoneum; Surgery

Treatments: Other: Peritoneum insufflation

Study type: Observational

Funder types: Other

Identifiers

NCT04468698

VoIPP

Details and patient eligibility

About

During pneumoperitoneum insufflation the insufflated gas increase intra-abdominal pressure. The generated pressure can lead to a different increase in volume depending on the abdominal cavity and patients' characteristics.

The primary objective is to determine the relationship between intraabdominal pressure (IAP) and intraabdominal volume (IAV) during pneumoperitoneum insufflation. The secondary objective is to determine the rate of abdominal-thoracic transmission (ATT) assessing the correlation between IAP and respiratory driving pressure (ΔPRS).

Enrollment: 204 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Enrolled one of the three studies (IPPCollapse I, II or III).
• underwent an initial insufflation procedure with a stepwise change in intraabdominal pressure to record Intraabdominal volume
• data from insufflation at 5 cmH2O of PEEP

Trial design

204 participants in 1 patient group

Global cohort

Description:

A global cohort is built merging data from three studies

Treatment:

Other: Peritoneum insufflation