Intra-articular Glucocorticoid Treatment of the Elbow

R

Region Gävleborg

Status

Completed

Conditions

Rheumatoid Arthritis

Treatments

Behavioral: immobilisation in a triangular sling

Study type

Interventional

Funder types

Other

Identifiers

NCT00972530
Dnr 2005:362

Details and patient eligibility

About

BACKGROUND: Intra-articular glucocorticoid injections are frequently used to relieve symptoms of arthritis. Postinjection rest has been shown to improve the outcome of knee joint injections, but not for wrist injections. Consequently, different joints respond differently on postinjection regimens. OBJECTIVES: To investigate whether better treatment results might be achieved of post-injection rest following intra-articular glucocorticoid treatment for elbow synovitis. METHODS: 90 patients with rheumatoid arthritis (RA) and elbow synovitis were treated with 20 mg intra-articular triamcinolone hexacetonide and randomised to either a 48 hour immobilisation in a triangular sling (n=46) or normal activity without restrictions (n=44). Primary endpoint was relapse of synovitis. In addition, pain, function according to a self assessment questionnaire (PREE) and range of movement were followed for six months.

Enrollment

90 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Rheumatoid arthritis, and
  • Clinical signs of elbow synovitis

Exclusion criteria

Patients in function class 4 according to Steinbrocker as well as patients with oral glucocorticoid treatment corresponding to more than 7.5 mg prednisolone or intra-articular treatment in the joint the past three months

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

90 participants in 2 patient groups

Activity
No Intervention group
Description:
Normal activity without restrictions
immobilisation
Active Comparator group
Description:
48 hours postinjection rest
Treatment:
Behavioral: immobilisation in a triangular sling

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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