Intra-Articular Injection of Etanercept in Patient Suffering From Rheumatoid Arthritis : a Double-Blind Randomized Study

Centre Hospitalier Universitaire de Nice

Status and phase: Completed; Phase 3

Conditions: Rheumatoid Arthritis

Treatments: Procedure: intra-articular injection of etanercept; Procedure: intra-articular injection of steroid

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT00522184

02-PP-04

Details and patient eligibility

About

Intra-articular injection of etanercept in patient suffering from rheumatoid arthritis: a double-blind randomized study for evaluation of efficacy and safety of etanercept versus intra-articular steroid injection in acute synovitis (knee,wrist,ankle,elbow)

Enrollment: 34 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• must be able to understand the information about the study
• diagnosis of rheumatoid arthritis for 6 month at least
• suffering for 2 weeks at least
• with evaluation of pain over 4/10
• with stable DMARDs treatment for three month at least

Exclusion criteria

• infection or surgery on the target joint
• treated with infliximab,adalimumab or anakinra

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

---

34 participants in 2 patient groups

1

Experimental group

Description:

patient receiving etanercept intra-articular injection

Treatment:

Procedure: intra-articular injection of etanercept

2

Active Comparator group

Description:

patient receiving steroid intra-articular injection

Treatment:

Procedure: intra-articular injection of steroid