Intra-articular Magnesium Sulfate for Tmj Dysfunction

Cairo University (CU)

Status and phase: Unknown; Early Phase 1

Conditions: Temporomandibular Sprain; Temporomandibular Joint Disorders

Treatments: Drug: intra-articular injection

Study type: Interventional

Funder types: Other

Identifiers

NCT03675659

CD5618

Details and patient eligibility

About

mixing the magnesium sulfate with dextrose for management of tmj pain will be studied using intra-articular injection of the solution

Enrollment: 100 estimated patients

Sex: Female

Ages: 20 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy females-no treatment received within the last 6 months-accept treatment protocol

Exclusion criteria

• unco-operative patients-patients with auto-immune diseases-patients diagnosed with arthritis

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

100 participants in 2 patient groups, including a placebo group

intra-articular injection

Active Comparator group

Description:

intra-articular injection with magnesium sulfate at weekly interval for four weeks

Treatment:

Drug: intra-articular injection

control

Placebo Comparator group

Description:

intra-articular injection with saline

Treatment:

Drug: intra-articular injection