Intra Cranial EEG Activity During Dexmedetomidine Sedation

University Health Network, Toronto

Status: Terminated

Conditions: Complex Partial Seizures

Treatments: Other: EEG Recording

Study type: Observational

Funder types: Other

Identifiers

NCT01648959

12-0268

Details and patient eligibility

About

Various parts of the brain are sensitive to various anesthetics.We like to study the effect of dexmedetomidine on the different parts of the brain in patients who are coming for DBS electrode removal under sedation.

Full description

Cortical and sub cortical structures will have different sensitivities to various anesthetics.The objective of this study is to look at the changes in the intracranial electroencephalographic (EEG) characteristics during dexmedetomidine sedation and to determine the differences in the EEG characteristics between cortical and subcortical structures.

Enrollment: 5 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults between 18 to 80 years of age, who are scheduled for elective removal of intracranial (surface and depth) electrodes under conscious sedation

Exclusion criteria

• Lack of informed consent
• Hypersensitivity to dexmedetomidine
• Language barrier
• Emergency surgery