Intra-individual Comparison of Conventional and Digital PET/CT Scanners

Isala

Status: Completed

Conditions: Breast Cancer; Esophageal Cancer; Miscellaneous Neoplasm; Lung Cancer

Treatments: Diagnostic Test: Digital PET/CT scan

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT03457506

NL52329.075.15

Details and patient eligibility

About

In this study, the investigators will analyze the impact of digital PET/CT on the final diagnostic conclusion of the scan in patients with lung cancer, breast cancer, esophageal cancer and a group of mescellaneous cancers.

Full description

There will be a single injection of the PET radiopharmaceutical FDG, followed by a conventional PET/CT scan and a digital PET scan, in this order or vice versa.

Enrollment: 225 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion criteria

In order to be eligible to participate in this study, a subject must meet all of the following criteria:

• referred to Isala for a clinically indicated FDG-PET/CT scan
• suspected or proven lung cancer, esophageal cancer, breast cancer or miscellaneous cancer, either as a primary diagnosis or follow-up study
• signed informed consent

Exclusion criteria

A potential subject who meets any of the following criteria will be excluded from participation in this study:

• age < 18 years
• incapacitated adults
• prisoners
• pregnant patients
• unable to undergo two consecutive PET/CT scans

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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225 participants in 1 patient group

Patients undergo a digital PET/CT

Other group

Description:

Single arm prospective study of paired PET scans. Patients who are referred to the nuclear medicine department to undergo a PET scan, will undergo a PET/CT scan on the conventional scanner as well as the digital PET/CT scanner.

Treatment:

Diagnostic Test: Digital PET/CT scan