Intra-pocket Application of Tea Tree Oil Gel in the Treatment of Stage-2 Periodontitis

Alexandria University

Status and phase

Completed

Phase 2

Conditions

Periodontitis

Treatments

Procedure: Scaling and Root Planing

Drug: Scaling and Root Planing with tea tree oil

Study type

Interventional

Funder types

Other

Identifiers

NCT04769271

Tea tree oil & periodontitis

Details and patient eligibility

About

This study aimed to assess clinically and biochemically the effect of intrapocket application of tea tree oil (TTO) gel adjunctive to SRP in the management of stage 2(moderate) periodontitis and to correlate the biochemical levels with clinical response.

Full description

A randomized, controlled clinical trial included thirty patients with stage 2 periodontitis. They were equally divided into two groups: Group 1 (control group) treated with scaling and root planning (SRP) alone and Group 2 (test group) managed by SRP and locally delivered 5% tea tree oil (TTO) gel.

Enrollment

30 patients

Sex

All

Ages

20 to 40 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients diagnosed with stage 2,grade B periodontitis according to the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions.
Patients with CAL 3-4 mm , BOP and radiographic horizontal bone loss related to the coronal third of the root (15%-33%).
Patients with no teeth loss due to periodontitis.
Patients with radiographic bone loss/age % of 0.25-1 %.
Patients who could maintain an O'Leary plaque index ≤10 proceeded into the study.

Exclusion criteria

Patients with CAL caused by non periodontal causes.
Patients with grade C periodontitis.
Patients having any systemic disease that may affect the treatment outcomes
Smokers.
Pregnant females.
Patients receiving contraindicated medications, chemotherapy, or radiotherapy in the previous year.