Intra Testicular Artery Injection of Bone Marrow Stem Cell in Management of Azoospermia

Man Clinic for Andrology, Male Infertility and Sexual Dysfunction

Status: Unknown

Conditions: Azoospermia

Treatments: Procedure: Bone marrow stem cell injection

Study type: Interventional

Funder types: Other

Identifiers

NCT02008799

SCA2013

Details and patient eligibility

About

Azoospermia due to low sperm production (non-obstructive azoospermia) affects approximately 1% of the male population and 10% of men who seek fertility evaluation. Testis biopsy reveals that these men have Sertoli cell-only pattern, maturation arrest, or hypospermatogenesis. Until recently, it was assumed that men with non-obstructive azoospermia were untreatable. Indeed, these patients were often referred to as being "sterile" or having "testicular failure." We start to use stem cell in treatment of such patients by injecting the stem cell at the testis and the testicular artery in one group and at the testis only in other group

Enrollment: 20 estimated patients

Sex: Male

Volunteers: No Healthy Volunteers

Inclusion criteria

• Azoospermia

Exclusion criteria

• Absent or surgical removed testes

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: Single Blind

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20 participants in 1 patient group

Bone marrow stem cell injection

Experimental group

Description:

through special butterfly inject stem cell in testicular artery and inside tubules

Treatment:

Procedure: Bone marrow stem cell injection